Direct Reprogramming of Mouse Fibroblasts to Neural Stem Cells by Small Molecules

• Główni autorzy: Yan-Chuang Han (Autor), Yoon Lim (Autor), Michael D. Duffieldl (Autor), Hua Li (Autor), Jia Liu (Autor), Nimshitha Pavathuparambil Abdul Manaph (Autor), Miao Yang (Autor), Damien J. Keating (Autor), Xin-Fu Zhou (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2016-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Although it is possible to generate neural stem cells (NSC) from somatic cells by reprogramming technologies with transcription factors, clinical utilization of patient-specific NSC for the treatment of human diseases remains elusive. The risk hurdles are associated with viral transduction vectors i...