Predicting and designing therapeutics against the Nipah virus.

• मुख्य लेखकों: Neeladri Sen (लेखक), Tejashree Rajaram Kanitkar (लेखक), Ankit Animesh Roy (लेखक), Neelesh Soni (लेखक), Kaustubh Amritkar (लेखक), Shreyas Supekar (लेखक), Sanjana Nair (लेखक), Gulzar Singh (लेखक), M S Madhusudhan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2019-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Despite Nipah virus outbreaks having high mortality rates (>70% in Southeast Asia), there are no licensed drugs against it. In this study, we have considered all 9 Nipah proteins as potential therapeutic targets and computationally identified 4 putative peptide inhibitors (against G, F and M prot...