Predicting and designing therapeutics against the Nipah virus.

• Egile Nagusiak: Neeladri Sen (Egilea), Tejashree Rajaram Kanitkar (Egilea), Ankit Animesh Roy (Egilea), Neelesh Soni (Egilea), Kaustubh Amritkar (Egilea), Shreyas Supekar (Egilea), Sanjana Nair (Egilea), Gulzar Singh (Egilea), M S Madhusudhan (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2019-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Despite Nipah virus outbreaks having high mortality rates (>70% in Southeast Asia), there are no licensed drugs against it. In this study, we have considered all 9 Nipah proteins as potential therapeutic targets and computationally identified 4 putative peptide inhibitors (against G, F and M prot...