Predicting and designing therapeutics against the Nipah virus.

• প্রধান লেখক: Neeladri Sen (লেখক), Tejashree Rajaram Kanitkar (লেখক), Ankit Animesh Roy (লেখক), Neelesh Soni (লেখক), Kaustubh Amritkar (লেখক), Shreyas Supekar (লেখক), Sanjana Nair (লেখক), Gulzar Singh (লেখক), M S Madhusudhan (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2019-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Despite Nipah virus outbreaks having high mortality rates (>70% in Southeast Asia), there are no licensed drugs against it. In this study, we have considered all 9 Nipah proteins as potential therapeutic targets and computationally identified 4 putative peptide inhibitors (against G, F and M prot...