The Multistage Antimalarial Compound Calxinin Perturbates <i>P. falciparum</i> Ca²⁺ Homeostasis by Targeting a Unique Ion Channel

• मुख्य लेखकों: Yash Gupta (लेखक), Neha Sharma (लेखक), Snigdha Singh (लेखक), Jesus G. Romero (लेखक), Vinoth Rajendran (लेखक), Reagan M. Mogire (लेखक), Mohammad Kashif (लेखक), Jordan Beach (लेखक), Walter Jeske (लेखक), Poonam (लेखक), Bernhards R. Ogutu (लेखक), Stefan M. Kanzok (लेखक), Hoseah M. Akala (लेखक), Jennifer Legac (लेखक), Philip J. Rosenthal (लेखक), David J. Rademacher (लेखक), Ravi Durvasula (लेखक), Agam P. Singh (लेखक), Brijesh Rathi (लेखक), Prakasha Kempaiah (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international collaborative team focuses on developing multistage antimalarials that exhibit novel mechanisms of action. Here, we describe the design, synthesis, and...