Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum

• Váldodahkkit: Alessandra Puddu (Dahkki), Roberta Sanguineti (Dahkki), Arianna Durante (Dahkki), Alessio Nencioni (Dahkki), François Mach (Dahkki), Fabrizio Montecucco (Dahkki), Giorgio L. Viviani (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2013-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Advanced glycation end products (AGEs) might play a pathophysiological role in the development of diabetes and its complications. AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin gene. Glucagon-like peptide-1 (GLP-1), an incretin h...