Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum

• Auteurs principaux: Alessandra Puddu (Auteur), Roberta Sanguineti (Auteur), Arianna Durante (Auteur), Alessio Nencioni (Auteur), François Mach (Auteur), Fabrizio Montecucco (Auteur), Giorgio L. Viviani (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2013-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Advanced glycation end products (AGEs) might play a pathophysiological role in the development of diabetes and its complications. AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin gene. Glucagon-like peptide-1 (GLP-1), an incretin h...