Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation

• Autores principales: Maria Camilla Operti (Autor), Alexander Bernhardt (Autor), Vladimir Sincari (Autor), Eliezer Jager (Autor), Silko Grimm (Autor), Andrea Engel (Autor), Martin Hruby (Autor), Carl Gustav Figdor (Autor), Oya Tagit (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2022-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Despite the efficacy and potential therapeutic benefits that poly(lactic-co-glycolic acid) (PLGA) nanomedicine formulations can offer, challenges related to large-scale processing hamper their clinical and commercial development. Major hurdles for the launch of a polymeric nanocarrier product on the...