Nitric Oxide Resistance in <i>Leishmania</i> (<i>Viannia</i>) <i>braziliensis</i> Involves Regulation of Glucose Consumption, Glutathione Metabolism and Abundance of Pentose Phosphate Pathway Enzymes

• 主要な著者: Nathalia Pinho (著者), Ana Cristina Bombaça (著者), Jacek R. Wiśniewski (著者), Geovane Dias-Lopes (著者), Leonardo Saboia-Vahia (著者), Elisa Cupolillo (著者), José Batista de Jesus (著者), Roque P. de Almeida (著者), Gabriel Padrón (著者), Rubem Menna-Barreto (著者), Patricia Cuervo (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In American Tegumentary Leishmaniasis production of cytokines, reactive oxygen species and nitric oxide (NO) by host macrophages normally lead to parasite death. However, some <i>Leishmania braziliensis</i> strains exhibit natural NO resistance. NO-resistant strains cause more lesions an...