Nitric Oxide Resistance in <i>Leishmania</i> (<i>Viannia</i>) <i>braziliensis</i> Involves Regulation of Glucose Consumption, Glutathione Metabolism and Abundance of Pentose Phosphate Pathway Enzymes

• Hoofdauteurs: Nathalia Pinho (Auteur), Ana Cristina Bombaça (Auteur), Jacek R. Wiśniewski (Auteur), Geovane Dias-Lopes (Auteur), Leonardo Saboia-Vahia (Auteur), Elisa Cupolillo (Auteur), José Batista de Jesus (Auteur), Roque P. de Almeida (Auteur), Gabriel Padrón (Auteur), Rubem Menna-Barreto (Auteur), Patricia Cuervo (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

In American Tegumentary Leishmaniasis production of cytokines, reactive oxygen species and nitric oxide (NO) by host macrophages normally lead to parasite death. However, some <i>Leishmania braziliensis</i> strains exhibit natural NO resistance. NO-resistant strains cause more lesions an...