Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

• Hauptverfasser: Burcu Çalışkan (VerfasserIn), Esra Sinoplu (VerfasserIn), Kübra İbiş (VerfasserIn), Ece Akhan Güzelcan (VerfasserIn), Rengül Çetin Atalay (VerfasserIn), Erden Banoglu (VerfasserIn)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

In our endeavour towards the development of effective anticancer therapeutics, a novel series of isoxazole-piperazine hybrids were synthesized and evaluated for their cytotoxic activities against human liver (Huh7 and Mahlavu) and breast (MCF-7) cancer cell lines. Within series, compounds 5l-o showe...