Zolpidem Activation of Alpha 1-Containing GABAA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons

• मुख्य लेखकों: Elena Neumann (लेखक), Uwe Rudolph (लेखक), Daniel E. Knutson (लेखक), Guanguan Li (लेखक), James M. Cook (लेखक), Harald Hentschke (लेखक), Bernd Antkowiak (लेखक), Berthold Drexler (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: High frequency neuronal activity in the cerebral cortex can be induced by noxious stimulation during surgery, brain injury or poisoning. In this scenario, it is essential to block cortical hyperactivity to protect the brain against damage, e.g., by using drugs that act as positive allo...