G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells

While technological advances in radiation oncology have led to a more precise delivery of radiation dose and a decreased risk of side effects, there is still a need to better understand the mechanisms underlying DNA damage response (DDR) at the DNA and cytogenetic levels, and to overcome tumor resis...

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Main Authors: Aggeliki Nikolakopoulou (Author), Aashish Soni (Author), Martha Habibi (Author), Pantelis Karaiskos (Author), Gabriel Pantelias (Author), Georgia I. Terzoudi (Author), George Iliakis (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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