G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells

• मुख्य लेखकों: Aggeliki Nikolakopoulou (लेखक), Aashish Soni (लेखक), Martha Habibi (लेखक), Pantelis Karaiskos (लेखक), Gabriel Pantelias (लेखक), Georgia I. Terzoudi (लेखक), George Iliakis (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

While technological advances in radiation oncology have led to a more precise delivery of radiation dose and a decreased risk of side effects, there is still a need to better understand the mechanisms underlying DNA damage response (DDR) at the DNA and cytogenetic levels, and to overcome tumor resis...