Betulinic Acid-Brosimine B Hybrid Compound Has a Synergistic Effect with Imatinib in Chronic Myeloid Leukemia Cell Line, Modulating Apoptosis and Autophagy

• Үндсэн зохиолчид: Julia Biz Willig (Зохиогч), Nádia Miléo Garcês de Couto (Зохиогч), Débora Renz Barreto Vianna (Зохиогч), Camila da Silveira Mariot (Зохиогч), Simone Cristina Baggio Gnoatto (Зохиогч), Andréia Buffon (Зохиогч), Diogo André Pilger (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-04-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by the formation of the BCR-ABL (breakpoint cluster region-Abelson) oncoprotein. As many patients display therapeutic resistance, the development of new drugs based on semisynthetic products represents a new potential thera...