Betulinic Acid-Brosimine B Hybrid Compound Has a Synergistic Effect with Imatinib in Chronic Myeloid Leukemia Cell Line, Modulating Apoptosis and Autophagy

• Päätekijät: Julia Biz Willig (Tekijä), Nádia Miléo Garcês de Couto (Tekijä), Débora Renz Barreto Vianna (Tekijä), Camila da Silveira Mariot (Tekijä), Simone Cristina Baggio Gnoatto (Tekijä), Andréia Buffon (Tekijä), Diogo André Pilger (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by the formation of the BCR-ABL (breakpoint cluster region-Abelson) oncoprotein. As many patients display therapeutic resistance, the development of new drugs based on semisynthetic products represents a new potential thera...