Chemotherapeutic Stress Induces Transdifferentiation of Glioblastoma Cells to Endothelial Cells and Promotes Vascular Mimicry

• Главные авторы: Shivani Baisiwala (Автор), Brenda Auffinger (Автор), Seamus P. Caragher (Автор), Jack M. Shireman (Автор), Riasat Ahsan (Автор), Gina Lee (Автор), Tanwir Hasan (Автор), Cheol Park (Автор), Miranda R. Saathoff (Автор), Anne C. Christensen (Автор), Atique U. Ahmed (Автор)
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• Опубликовано: Hindawi Limited, 2019-01-01T00:00:00Z.
• Предметы: article
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Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor affecting adults, with a median survival of approximately 21 months. One key factor underlying the limited efficacy of current treatment modalities is the remarkable plasticity exhibited by GBM cells, which allows the...