<i>ERCC1</i> and <i>ERCC2</i> Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer

<i>ERCC1</i> and <i>ERCC2</i> Polymorphisms Predict the Efficacy and Toxicity of Platinum-Based Chemotherapy in Small Cell Lung Cancer

Standard first-line chemotherapy in small cell lung cancer (SCLC) is based on the platinum plus etoposide combination. Despite a high objective response rate, responses are not durable and chemotherapy-induced toxicity may compromise treatment. Genetic variants in genes involved in the DNA-repair pa...

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Main Authors: Andrés Barba (Author), Laura López-Vilaró (Author), Malena Ferre (Author), Margarita Majem (Author), Sergio Martinez-Recio (Author), Olga Bell (Author), María J. Arranz (Author), Juliana Salazar (Author), Ivana Sullivan (Author)
Format: Book
Published: MDPI AG, 2024-08-01T00:00:00Z.
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