Pharmacokinetic and pharmacodynamic assessments of atogepant in healthy male adults: Results from phase 1 studies

• Главные авторы: Ramesh Boinpally (Автор), Marleen Depré (Автор), Griet Van Lancker (Автор), Marissa F Dockendorf (Автор), Phung Bondiskey (Автор), Jean-Francois Denef (Автор), Tom Reynders (Автор), Catherine Zhou Matthews (Автор), K Chris Min (Автор), Jialin Xu (Автор), Joel M Trugman (Автор), Jan de Hoon (Автор)
• Формат: ‌
• Опубликовано: SAGE Publishing, 2023-08-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Background/Hypothesis: Atogepant, an oral calcitonin gene-related peptide receptor antagonist, is approved for the preventive treatment of migraine in adults. This manuscript characterizes the safety, tolerability, pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of atogepant in hea...