AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia

• मुख्य लेखकों: Lingying Tong (लेखक), Burcak Ozes (लेखक), Kyle Moss (लेखक), Morgan Myers (लेखक), Alicia Ridgley (लेखक), Zarife Sahenk (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2023-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Sarcopenia, an age‐related loss of muscle mass, is a critical factor that affects the health of the older adults. The SOD1KO mouse is deficient of Cu/Zn superoxide dismutase, used as an accelerated aging model. We previously showed that NT‐3 improves muscle fibre size by activati...