AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia

• Main Authors: Lingying Tong (Author), Burcak Ozes (Author), Kyle Moss (Author), Morgan Myers (Author), Alicia Ridgley (Author), Zarife Sahenk (Author)
• Formato: Livro
• Publicado em: Wiley, 2023-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Sarcopenia, an age‐related loss of muscle mass, is a critical factor that affects the health of the older adults. The SOD1KO mouse is deficient of Cu/Zn superoxide dismutase, used as an accelerated aging model. We previously showed that NT‐3 improves muscle fibre size by activati...