Metformin ameliorates olanzapine-induced obesity and glucose intolerance by regulating hypothalamic inflammation and microglial activation in female mice

• Główni autorzy: Sang Bum Suh (Autor), Nayoung Lee (Autor), Jaedeok Kim (Autor), Saeha Kim (Autor), Sooyeon Jang (Autor), Jong Kook Park (Autor), Keunwook Lee (Autor), Soo Young Choi (Autor), Hyung-Joo Kwon (Autor), Chan Hee Lee (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Olanzapine (OLZ), a widely used second-generation antipsychotic drug, is known to cause metabolic side effects, including diabetes and obesity. Interestingly, OLZ-induced metabolic side effects have been demonstrated to be more profound in females in human studies and animal models. Metformin (MET)...