Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death

• Päätekijät: Haruna Ebisu (Tekijä), Kana Shintani (Tekijä), Takumi Chinen (Tekijä), Yoko Nagumo (Tekijä), Shuya Shioda (Tekijä), Taisei Hatanaka (Tekijä), Akira Sakakura (Tekijä), Ichiro Hayakawa (Tekijä), Hideo Kigoshi (Tekijä), Takeo Usui (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

α/β-Tubulin inhibitors that alter microtubule (MT) dynamics are commonly used in cancer therapy, however, these inhibitors also cause severe side effects such as peripheral neuropathy. γ-Tubulin is a possible target as antitumor drugs with low side effects, but the antitumor effect of γ-tubulin inhi...