Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death

• Κύριοι συγγραφείς: Haruna Ebisu (Συγγραφέας), Kana Shintani (Συγγραφέας), Takumi Chinen (Συγγραφέας), Yoko Nagumo (Συγγραφέας), Shuya Shioda (Συγγραφέας), Taisei Hatanaka (Συγγραφέας), Akira Sakakura (Συγγραφέας), Ichiro Hayakawa (Συγγραφέας), Hideo Kigoshi (Συγγραφέας), Takeo Usui (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

α/β-Tubulin inhibitors that alter microtubule (MT) dynamics are commonly used in cancer therapy, however, these inhibitors also cause severe side effects such as peripheral neuropathy. γ-Tubulin is a possible target as antitumor drugs with low side effects, but the antitumor effect of γ-tubulin inhi...