Repurposed Drugs That Activate Autophagy in Filarial Worms Act as Effective Macrofilaricides

• 主要な著者: Denis Voronin (著者), Nancy Tricoche (著者), Ricardo Peguero (著者), Anna Maria Kaminska (著者), Elodie Ghedin (著者), Judy A. Sakanari (著者), Sara Lustigman (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Onchocerciasis and lymphatic filariasis are two neglected tropical diseases caused by filarial nematodes that utilize insect vectors for transmission to their human hosts. Current control strategies are based on annual or biannual mass drug administration (MDA) of the drugs Ivermectin or Ivermectin...