Repurposed Drugs That Activate Autophagy in Filarial Worms Act as Effective Macrofilaricides

• Main Authors: Denis Voronin (Author), Nancy Tricoche (Author), Ricardo Peguero (Author), Anna Maria Kaminska (Author), Elodie Ghedin (Author), Judy A. Sakanari (Author), Sara Lustigman (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Onchocerciasis and lymphatic filariasis are two neglected tropical diseases caused by filarial nematodes that utilize insect vectors for transmission to their human hosts. Current control strategies are based on annual or biannual mass drug administration (MDA) of the drugs Ivermectin or Ivermectin...