Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells

Abstract Background Infertility affects approximately 10-15% of reproductive-age men worldwide, and genetic causes play a role in one-third of cases. As a Bin-Amphiphysin-Rvs (BAR) domain protein, protein interacting with C-kinase 1 (PICK1) deficiency could lead to impairment of acrosome maturation....

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Main Authors: Jing Jin (Author), Kaiqiang Li (Author), Yaoqiang Du (Author), Fang Gao (Author), Zhen Wang (Author), Weixing Li (Author)
Format: Book
Published: BMC, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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