Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells

• Asıl Yazarlar: Jing Jin (Yazar), Kaiqiang Li (Yazar), Yaoqiang Du (Yazar), Fang Gao (Yazar), Zhen Wang (Yazar), Weixing Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2023-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Infertility affects approximately 10-15% of reproductive-age men worldwide, and genetic causes play a role in one-third of cases. As a Bin-Amphiphysin-Rvs (BAR) domain protein, protein interacting with C-kinase 1 (PICK1) deficiency could lead to impairment of acrosome maturation....