Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

• প্রধান লেখক: J.D. Gothié (লেখক), A. Sébillot (লেখক), C. Luongo (লেখক), M. Legendre (লেখক), C. Nguyen Van (লেখক), K. Le Blay (লেখক), M. Perret-Jeanneret (লেখক), S. Remaud (লেখক), B.A. Demeneix (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2017-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Objective: In the adult brain, neural stem cells (NSCs) located in the subventricular zone (SVZ) produce both neuronal and glial cells. Thyroid hormones (THs) regulate adult NSC differentiation towards a neuronal phenotype, but also have major roles in mitochondrial metabolism. As NSC metabolism rel...