Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis

• मुख्य लेखकों: Shaza Asif (लेखक), Ri Youn Kim (लेखक), Thet Fatica (लेखक), Jordan Sim (लेखक), Xiaoling Zhao (लेखक), Yena Oh (लेखक), Alix Denoncourt (लेखक), Angela C. Cheung (लेखक), Michael Downey (लेखक), Erin E. Mulvihill (लेखक), Kyoung-Han Kim (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Aberrant ketogenesis is correlated with the degree of steatosis in non-alcoholic fatty liver disease (NAFLD) patients, and an inborn error of ketogenesis (mitochondrial HMG-CoA synthase deficiency) is commonly associated with the development of the fatty liver. Here we aimed to determine...