Potent and selective inhibitors for M32 metallocarboxypeptidases identified from high-throughput screening of anti-kinetoplastid chemical boxes.

Enzymes of the M32 family are Zn-dependent metallocarboxypeptidases (MCPs) widely distributed among prokaryotic organisms and just a few eukaryotes including Trypanosoma brucei and Trypanosoma cruzi, the causative agents of sleeping sickness and Chagas disease, respectively. These enzymes are absent...

Full description

Saved in:
Bibliographic Details
Main Authors: Emir Salas-Sarduy (Author), Lionel Urán Landaburu (Author), Adriana K Carmona (Author), Juan José Cazzulo (Author), Fernán Agüero (Author), Vanina E Alvarez (Author), Gabriela T Niemirowicz (Author)
Format: Book
Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available