Factors affecting low fetal fraction in fetal screening with cell-free DNA in pregnant women: a systematic review and meta-analysis

Factors affecting low fetal fraction in fetal screening with cell-free DNA in pregnant women: a systematic review and meta-analysis

Abstract Background Cell-Free DNA (cfDNA) is a non-invasive perinatal test (NIPT) used to assess fetal anomalies. The ability to detect fetal chromosomal aneuploidies is directly related to a sample's fetal to total DNA fraction, known as the fetal fraction (FF). The minimum FF is considered 4%...

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Main Authors: Sanaz Mousavi (Author), Ziba Shokri (Author), Parvin Bastani (Author), Morteza Ghojazadeh (Author), Sevda Riahifar (Author), Hooman Nateghian (Author)
Format: Book
Published: BMC, 2022-12-01T00:00:00Z.
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