Factors affecting low fetal fraction in fetal screening with cell-free DNA in pregnant women: a systematic review and meta-analysis

• Główni autorzy: Sanaz Mousavi (Autor), Ziba Shokri (Autor), Parvin Bastani (Autor), Morteza Ghojazadeh (Autor), Sevda Riahifar (Autor), Hooman Nateghian (Autor)
• Format: Książka
• Wydane: BMC, 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Cell-Free DNA (cfDNA) is a non-invasive perinatal test (NIPT) used to assess fetal anomalies. The ability to detect fetal chromosomal aneuploidies is directly related to a sample's fetal to total DNA fraction, known as the fetal fraction (FF). The minimum FF is considered 4%...