New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis

• 主要な著者: Luc H. Boudreau (著者), Grégoire Lassalle-Claux (著者), Marc Cormier (著者), Sébastien Blanchard (著者), Marco S. Doucet (著者), Marc E. Surette (著者), Mohamed Touaibia (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2017-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Leukotrienes are inflammatory mediators that actively participate in the inflammatory response and host defense against pathogens. However, leukotrienes also participate in chronic inflammatory diseases. 5-lipoxygenase is a key enzyme in the biosynthesis of leukotrienes and is thus a validated thera...