Population Pharmacokinetics of Polymyxin B in Obese Patients for Resistant Gram-Negative Infections

• 主要な著者: Peile Wang (著者), Qiwen Zhang (著者), Min Feng (著者), Tongwen Sun (著者), Jing Yang (著者), Xiaojian Zhang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Polymyxin B is an effective but potentially nephrotoxic antibiotic that is commonly used to treat resistant Gram-negative infections. As a weight-based dosing drug, obese patients may be at a high risk of nephrotoxicity. However, the pharmacokinetics and dosing recommendations for this population ar...