Constitutively Active Mutant N111G of Angiotensin II Type 1 (AT1) Receptor Induces Homologous Internalization Through Mediation of AT1-Receptor Antagonist

• Hoofdauteurs: Mohiuddin Ahmed Bhuiyan (Auteur), Murad Hossain (Auteur), Shin-ichiro Miura (Auteur), Takashi Nakamura (Auteur), Masanobu Ozaki (Auteur), Takafumi Nagatomo (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2009-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The present study investigated the internalization behavior of the constitutively active mutant (CAM) N111G of angiotensin II type 1 (AT1) receptor and correlated the result with the mechanism of the constitutive activity of the mutant. The inverse agonist activity of valsartan, losartan, candesarta...