Constitutively Active Mutant N111G of Angiotensin II Type 1 (AT1) Receptor Induces Homologous Internalization Through Mediation of AT1-Receptor Antagonist

• 主要な著者: Mohiuddin Ahmed Bhuiyan (著者), Murad Hossain (著者), Shin-ichiro Miura (著者), Takashi Nakamura (著者), Masanobu Ozaki (著者), Takafumi Nagatomo (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2009-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The present study investigated the internalization behavior of the constitutively active mutant (CAM) N111G of angiotensin II type 1 (AT1) receptor and correlated the result with the mechanism of the constitutive activity of the mutant. The inverse agonist activity of valsartan, losartan, candesarta...