Mechanistic insights into MARK4 inhibition by galantamine toward therapeutic targeting of Alzheimer's disease

• 主要な著者: Mohd Adnan (著者), Debarati DasGupta (著者), Saleha Anwar (著者), Anas Shamsi (著者), Arif Jamal Siddiqui (著者), Mejdi Snoussi (著者), Fevzi Bardakci (著者), Mitesh Patel (著者), Md Imtaiyaz Hassan (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: Hyperphosphorylation of tau is an important event in Alzheimer's disease (AD) pathogenesis, leading to the generation of "neurofibrillary tangles," a histopathological hallmark associated with the onset of AD and related tauopathies. Microtubule-affinity regulating kinas...