Mechanistic insights into MARK4 inhibition by galantamine toward therapeutic targeting of Alzheimer's disease

• Main Authors: Mohd Adnan (Author), Debarati DasGupta (Author), Saleha Anwar (Author), Anas Shamsi (Author), Arif Jamal Siddiqui (Author), Mejdi Snoussi (Author), Fevzi Bardakci (Author), Mitesh Patel (Author), Md Imtaiyaz Hassan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Hyperphosphorylation of tau is an important event in Alzheimer's disease (AD) pathogenesis, leading to the generation of "neurofibrillary tangles," a histopathological hallmark associated with the onset of AD and related tauopathies. Microtubule-affinity regulating kinas...