Extracellular CIRP induces CD4CD8αα intraepithelial lymphocyte cytotoxicity in sepsis

• मुख्य लेखकों: Yuichi Akama (लेखक), Atsushi Murao (लेखक), Monowar Aziz (लेखक), Ping Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background In sepsis, intestinal barrier dysfunction is often caused by the uncontrolled death of intestinal epithelial cells (IECs). CD4CD8αα intraepithelial lymphocytes (IELs), a subtype of CD4+ T cells residing within the intestinal epithelium, exert cytotoxicity by producing granzyme B...