Extracellular CIRP induces CD4CD8αα intraepithelial lymphocyte cytotoxicity in sepsis
Abstract Background In sepsis, intestinal barrier dysfunction is often caused by the uncontrolled death of intestinal epithelial cells (IECs). CD4CD8αα intraepithelial lymphocytes (IELs), a subtype of CD4+ T cells residing within the intestinal epithelium, exert cytotoxicity by producing granzyme B...
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2024-02-01T00:00:00Z.
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