Antifungal Activity of Amphotericin B Conjugated to Nanosized Magnetite in the Treatment of Paracoccidioidomycosis.

• Главные авторы: Camila Arruda Saldanha (Автор), Mônica Pereira Garcia (Автор), Diego Cesar Iocca (Автор), Luciana Guilherme Rebelo (Автор), Ana Camila Oliveira Souza (Автор), Anamélia Lorenzetti Bocca (Автор), Maria de Fátima Menezes Almeida Santos (Автор), Paulo Cesar Morais (Автор), Ricardo Bentes Azevedo (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2016-06-01T00:00:00Z.
• Предметы: article
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This study reports on in vitro and in vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising amphotericin B loaded onto the surface of pre-coated (with a double-layer of lauric acid) magnetite nanoparticles. The in vitro tests compared two dr...