Antifungal Activity of Amphotericin B Conjugated to Nanosized Magnetite in the Treatment of Paracoccidioidomycosis.

• Hauptverfasser: Camila Arruda Saldanha (Verfasst von), Mônica Pereira Garcia (Verfasst von), Diego Cesar Iocca (Verfasst von), Luciana Guilherme Rebelo (Verfasst von), Ana Camila Oliveira Souza (Verfasst von), Anamélia Lorenzetti Bocca (Verfasst von), Maria de Fátima Menezes Almeida Santos (Verfasst von), Paulo Cesar Morais (Verfasst von), Ricardo Bentes Azevedo (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2016-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

This study reports on in vitro and in vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising amphotericin B loaded onto the surface of pre-coated (with a double-layer of lauric acid) magnetite nanoparticles. The in vitro tests compared two dr...