NRF2, a Superstar of Ferroptosis

• Main Authors: Ruihan Yan (Author), Bingyi Lin (Author), Wenwei Jin (Author), Ling Tang (Author), Shuming Hu (Author), Rong Cai (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is an iron-dependent and lipid peroxidation-driven cell death cascade, occurring when there is an imbalance of redox homeostasis in the cell. Nuclear factor erythroid 2-related factor 2 (NFE2L2, also known as NRF2) is key for cellular antioxidant responses, which promotes downstream gene...