NRF2, a Superstar of Ferroptosis

• Autori principali: Ruihan Yan (Autore), Bingyi Lin (Autore), Wenwei Jin (Autore), Ling Tang (Autore), Shuming Hu (Autore), Rong Cai (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Ferroptosis is an iron-dependent and lipid peroxidation-driven cell death cascade, occurring when there is an imbalance of redox homeostasis in the cell. Nuclear factor erythroid 2-related factor 2 (NFE2L2, also known as NRF2) is key for cellular antioxidant responses, which promotes downstream gene...