Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats

• Главные авторы: Felipe Patricio (Автор), Eliud Morales Dávila (Автор), Aleidy Patricio-Martínez (Автор), Nayeli Arana Del Carmen (Автор), Isabel Martínez (Автор), José Aguilera (Автор), Jose Manuel Perez-Aguilar (Автор), Ilhuicamina Daniel Limón (Автор)
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• Опубликовано: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Предметы: article
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Cannabidiol (CBD) presents antiparkinsonian properties and neuromodulatory effects, possibly due to the pleiotropic activity caused at multiple molecular targets. Recently, the GPR55 receptor has emerged as a molecular target of CBD. Interestingly, GPR55 mRNA is expressed in the external globus pall...