Targeting Gremlin 1 Prevents Intestinal Fibrosis Progression by Inhibiting the Fatty Acid Oxidation of Fibroblast Cells

• Κύριοι συγγραφείς: Yang Yang (Συγγραφέας), Qi-Shan Zeng (Συγγραφέας), Min Zou (Συγγραφέας), Jian Zeng (Συγγραφέας), Jiao Nie (Συγγραφέας), DongFeng Chen (Συγγραφέας), Hua-Tian Gan (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Intestinal fibrosis is a consequence of continuous inflammatory responses that negatively affect the quality of life of patients. By screening altered proteomic profiles of mouse fibrotic colon tissues, we identified that GREM1 was dramatically upregulated in comparison to that in normal tissues. Fu...