Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer

• मुख्य लेखकों: Alsmawal A. Elimam (लेखक), Mohamed Elmogtba Mouaweia Mohamed Aabdein (लेखक), Mohamed El-Fatih Moly Eldeen (लेखक), Hisham N. Altayb (लेखक), Mohamed Adel Taha (लेखक), Mohammed N. Nimir (लेखक), Mohamed D. Dafaalla (लेखक), Musaab M. Alfaki (लेखक), Mohamed A. Abdelrahim (लेखक), Abdelmohaymin A. Abdalla (लेखक), Musab I. Mohammed (लेखक), Mona Ellaithi (लेखक), Muzamil Mahdi Abdel Hamid (लेखक), Mohamed Ahmed Salih Hassan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2017-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Breast cancer (BC) is the most common type of cancer in women. Among many risk factors of BC, mutations in BRCA2 gene were found to be the primary cause in 5-10% of cases. The majority of deleterious mutations are frameshift or nonsense mutations. Most of the reported BRCA2 mutat...