Modulation of Multiple Gene Clusters' Expression by the PAS-LuxR Transcriptional Regulator PteF

• প্রধান লেখক: Cláudia M. Vicente (লেখক), Tamara D. Payero (লেখক), Antonio Rodríguez-García (লেখক), Eva G. Barreales (লেখক), Antonio de Pedro (লেখক), Fernando Santos-Beneit (লেখক), Jesús F. Aparicio (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2022-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from <i>Streptomyces avermitilis</i>. Its mutation drastically abates filipin, but also oligomycin production, a macrolide ATP-synthase inhi...