Modulation of Multiple Gene Clusters' Expression by the PAS-LuxR Transcriptional Regulator PteF

• Autores principales: Cláudia M. Vicente (Autor), Tamara D. Payero (Autor), Antonio Rodríguez-García (Autor), Eva G. Barreales (Autor), Antonio de Pedro (Autor), Fernando Santos-Beneit (Autor), Jesús F. Aparicio (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2022-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from <i>Streptomyces avermitilis</i>. Its mutation drastically abates filipin, but also oligomycin production, a macrolide ATP-synthase inhi...