Modulation of Multiple Gene Clusters' Expression by the PAS-LuxR Transcriptional Regulator PteF

• मुख्य लेखकों: Cláudia M. Vicente (लेखक), Tamara D. Payero (लेखक), Antonio Rodríguez-García (लेखक), Eva G. Barreales (लेखक), Antonio de Pedro (लेखक), Fernando Santos-Beneit (लेखक), Jesús F. Aparicio (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from <i>Streptomyces avermitilis</i>. Its mutation drastically abates filipin, but also oligomycin production, a macrolide ATP-synthase inhi...