The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats

• Asıl Yazarlar: Vladimír Sobota (Yazar), Giulia Gatta (Yazar), Arne van Hunnik (Yazar), Iris van Tuijn (Yazar), Marion Kuiper (Yazar), James Milnes (Yazar), Thomas Jespersen (Yazar), Ulrich Schotten (Yazar), Sander Verheule (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Konular: article
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Aims: The acetylcholine-activated inward rectifier potassium current (IKACh) has been proposed as an atrial-selective target for the treatment of atrial fibrillation (AF). Using a novel selective IKACh inhibitor XAF-1407, the study investigates the effect of IKACh inhibition in goats with pacing-ind...