Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT_1A Receptor Biased Agonist

• Autors principals: Sharon Cabanu (Autor), Fuencisla Pilar-Cuéllar (Autor), Paula Zubakina (Autor), Eva Florensa-Zanuy (Autor), Júlia Senserrich (Autor), Adrian Newman-Tancredi (Autor), Albert Adell (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT_1A receptors have attracted interest as targets for therapeutic interv...