Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT_1A Receptor Biased Agonist

• Главные авторы: Sharon Cabanu (Автор), Fuencisla Pilar-Cuéllar (Автор), Paula Zubakina (Автор), Eva Florensa-Zanuy (Автор), Júlia Senserrich (Автор), Adrian Newman-Tancredi (Автор), Albert Adell (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT_1A receptors have attracted interest as targets for therapeutic interv...