Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT_1A Receptor Biased Agonist

• Main Authors: Sharon Cabanu (Author), Fuencisla Pilar-Cuéllar (Author), Paula Zubakina (Author), Eva Florensa-Zanuy (Author), Júlia Senserrich (Author), Adrian Newman-Tancredi (Author), Albert Adell (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT_1A receptors have attracted interest as targets for therapeutic interv...